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The development and application of a risk prediction model for extracorporeal circuit clotting during continuous renal replacement therapy
HU Lulu, NIU Hongyan, HAN Xiaoyun, ZHU Xiying, LIU Jinfeng
Chinese Journal of Nursing    2023, 58 (15): 1845-1851.   DOI: 10.3761/j.issn.0254-1769.2023.15.009
Abstract360)   HTML3)    PDF (874KB)(28)       Save

Objective To construct and verify a predictive model to assess the risk of extracorporeal circuit clotting during continuous renal replacement therapy(CRRT). Methods A total of 320 patients with CRRT were enrolled from April 2021 to January 2022,and risk factors between a blockage group(222 cases) and a non-blockage group(98 cases) were compared using logistic regression for model construction. The goodness of fit of the model was verified by Hosmer-Lemeshow test. The predictive validity of the model was evaluated by the area under the ROC curve. From February to June 2022,160 patients were recruited for application of the model. Results The incidence of coagulation in this study was 30.6%. The factors that ultimately entered the predictive model were CVVHD mode of treatment(OR=2.482),CVVH mode of treatment(OR=2.724),citrate anticoagulation(OR=3.425),argatroban(OR=3.150),without anticoagulation(OR=9.103),pump interruption(OR=4.114),access outflow dysfunction(OR=2.769),the platelet count(OR=1.005),and APTT(OR=0.859). The model formula was P=1/[1+exp(-0.866+0.909 × CVVHD+1.002 × CVVH+1.231×citrate anticoagulation+1.147 × argatroban+2.209 × without anticoagulation+1.415 × pump interruption+1.018 × access outflow dysfunction+0.005 × the platelet count-0.152 × APTT)]. The area under the ROC curve was 0.865,while the Youden index was 0.584,with sensitivity of 75.50% and specificity of 82.90%. The model verification results showed the sensitivity of 84.10%,the specificity of 79.31%,and the accuracy of 80.63%. Conclusion The risk prediction model has satisfactory prediction effects. The risk prediction can be completed at the beginning of CRRT,which can provide references for preventative treatment and nursing measures for high-risk patients.

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Translation and test of validation and reliability of Inflammatory Bowel Diseases Disk Scale
LIU Jinfeng, JIANG Qiuxia, LIU Alan, LIU Juan, BAN Chunjing
Chinese Journal of Nursing    2022, 57 (5): 635-640.   DOI: 10.3761/j.issn.0254-1769.2022.05.019
Abstract526)   HTML0)    PDF (764KB)(6)       Save

Objective To sinicize the Inflammatory Bowel Diseases Disk (IBD-disk) Scale into Chinese,and to test the reliability and validity of the scale. Methods Through literal translation,back translation,expert discussion and evaluation and cross-cultural debugging of the scale in English,2 researchers finally formed the IBD-disk Scale in Chinese. 315 patients with inflammatory bowel disease who were followed up in the outpatient department of a tertiary A general hospital in Anhui province from June 2021 to August 2021 were selected as the research subjects. 4 weeks later,48 patients were selected by a random number table method for retesting. Results The Chinese scale contains 10 items,and the correlation coefficients between the scores of each item and the total score of the scale were 0.630~0.816(P<0.001). The CR values of 10 items were 4.79~30.93 with statistically significant differences(P<0.001);exploratory and confirmatory factor analysis supported the one-dimensional nature of the scale,and the fit was good. The internal consistency coefficient was 0.895,and the retest reliability was 0.861,which indicated that the data reliability and quality was good. There was a positive correlation between IBD-Disk Scale and IBD Burden of Disease Scale(r=-0.513,P<0.001). Conclusion The Chinese version of IBD-Disk Scale has good reliability and validity,and it can be used as a tool to evaluate the degree of disability in patients with inflammatory bowel disease.

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